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Inhibitory Effect of Sirtuin6 (SIRT6) on Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells

BACKGROUND: The imbalance between bone resorption and formation is the basic mechanism underlying osteoporosis in the elderly. Osteogenesis is the differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts. Sirtuin6 (SIRT6) regulates various biological functions, including differentiat...

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Zhou, Yun, Liu, Yongfu, Xie, Mian, Guo, Guancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858786/
https://www.ncbi.nlm.nih.gov/pubmed/31701920
http://dx.doi.org/10.12659/MSM.917118