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House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation
Allergic skin diseases, such as atopic dermatitis (AD), are clinically characterized by severe itching and type 2 immunity-associated hypersensitivity to widely-distributed allergens, including those derived from house dust mites (HDMs). Here we found that HDMs with cysteine-protease activity direct...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858877/ https://www.ncbi.nlm.nih.gov/pubmed/31591569 http://dx.doi.org/10.1038/s41590-019-0493-z |