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Inducing and exploiting vulnerabilities for the treatment of liver cancer

Liver cancer remains difficult to treat due to a paucity of drugs that target critical dependencies(1,2) and broad spectrum kinase inhibitors like sorafenib provide only modest benefit to hepatocellular carcinoma (HCC) patients(3). Induction of senescence may represent a promising strategy for the t...

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Detalles Bibliográficos
Autores principales:	Wang, Cun, Vegna, Serena, Jin, Haojie, Benedict, Bente, Lieftink, Cor, Ramirez, Christel, Leite de Oliveira, Rodrigo, Morris, Ben, Gadiot, Jules, Wang, Wei, du Chatinier, Aimée, Wang, Liqin, Gao, Dongmei, Evers, Bastiaan, Jin, Guangzhi, Xue, Zheng, Schepers, Arnout, Jochems, Fleur, Mulero Sanchez, Antonio, Mainardi, Sara, te Riele, Hein, Beijersbergen, Roderick L., Qin, Wenxin, Akkari, Leila, Bernards, René
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858884/ https://www.ncbi.nlm.nih.gov/pubmed/31578521 http://dx.doi.org/10.1038/s41586-019-1607-3

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