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A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016
Brucella serostatus was evaluated in 3189 muskoxen sampled between 1989 and 2016 from various locations of the Canadian Arctic archipelago and mainland, near the communities of Sachs Harbour and Ulukhaktok, Northwest Territories, and Cambridge Bay and Kugluktuk, Nunavut. Brucella antibodies were fou...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858907/ https://www.ncbi.nlm.nih.gov/pubmed/31414318 http://dx.doi.org/10.1007/s10393-019-01433-3 |
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author | Tomaselli, Matilde Elkin, Brett Kutz, Susan Harms, N. Jane Nymo, H. Ingebjørg Davison, Tracy Leclerc, Lisa-Marie Branigan, Marsha Dumond, Mathieu Tryland, Morten Checkley, Sylvia |
author_facet | Tomaselli, Matilde Elkin, Brett Kutz, Susan Harms, N. Jane Nymo, H. Ingebjørg Davison, Tracy Leclerc, Lisa-Marie Branigan, Marsha Dumond, Mathieu Tryland, Morten Checkley, Sylvia |
author_sort | Tomaselli, Matilde |
collection | PubMed |
description | Brucella serostatus was evaluated in 3189 muskoxen sampled between 1989 and 2016 from various locations of the Canadian Arctic archipelago and mainland, near the communities of Sachs Harbour and Ulukhaktok, Northwest Territories, and Cambridge Bay and Kugluktuk, Nunavut. Brucella antibodies were found only in muskoxen sampled around Cambridge Bay, both on southern Victoria Island and on the adjacent mainland (Kent Peninsula). Consistent with participatory epidemiology data documented from local harvesters describing increased Brucella-like syndromes (swollen joints and lameness) and a decreased proportion of juveniles, the apparent Brucella seroprevalence in the sampled muskoxen of the Cambridge Bay area increased from 0.9% (95% CI 0.3–2.1) in the period of 1989–2001 to 5.6% (95% CI 3.3–8.9) in 2010–2016. The zoonotic bacteria Brucella suis biovar 4 was also cultured from tissues of muskoxen sampled on Victoria Island near Ulukhaktok in 1996 (n = 1) and Cambridge Bay in 1998, 2014, and 2016 (n = 3). Overall, our data demonstrate that B. suis biovar 4 is found in muskoxen that are harvested for food and by guided hunts on Victoria Island and Kent Peninsula, adding an important public health dimension to this study. Robust participatory epidemiology data on muskox health and diseases greatly enhanced the interpretation of our Cambridge Bay data and, combined with the serological and microbiological data, provide compelling evidence that the prevalence of B. suis biovar 4 has increased in this area since the late 1990s. This study enhances the available knowledge on Brucella exposure and infection in muskoxen and provides an example of how scientific knowledge and local knowledge can work together to better understand disease status in wildlife. |
format | Online Article Text |
id | pubmed-6858907 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-68589072019-12-03 A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016 Tomaselli, Matilde Elkin, Brett Kutz, Susan Harms, N. Jane Nymo, H. Ingebjørg Davison, Tracy Leclerc, Lisa-Marie Branigan, Marsha Dumond, Mathieu Tryland, Morten Checkley, Sylvia Ecohealth Original Contribution Brucella serostatus was evaluated in 3189 muskoxen sampled between 1989 and 2016 from various locations of the Canadian Arctic archipelago and mainland, near the communities of Sachs Harbour and Ulukhaktok, Northwest Territories, and Cambridge Bay and Kugluktuk, Nunavut. Brucella antibodies were found only in muskoxen sampled around Cambridge Bay, both on southern Victoria Island and on the adjacent mainland (Kent Peninsula). Consistent with participatory epidemiology data documented from local harvesters describing increased Brucella-like syndromes (swollen joints and lameness) and a decreased proportion of juveniles, the apparent Brucella seroprevalence in the sampled muskoxen of the Cambridge Bay area increased from 0.9% (95% CI 0.3–2.1) in the period of 1989–2001 to 5.6% (95% CI 3.3–8.9) in 2010–2016. The zoonotic bacteria Brucella suis biovar 4 was also cultured from tissues of muskoxen sampled on Victoria Island near Ulukhaktok in 1996 (n = 1) and Cambridge Bay in 1998, 2014, and 2016 (n = 3). Overall, our data demonstrate that B. suis biovar 4 is found in muskoxen that are harvested for food and by guided hunts on Victoria Island and Kent Peninsula, adding an important public health dimension to this study. Robust participatory epidemiology data on muskox health and diseases greatly enhanced the interpretation of our Cambridge Bay data and, combined with the serological and microbiological data, provide compelling evidence that the prevalence of B. suis biovar 4 has increased in this area since the late 1990s. This study enhances the available knowledge on Brucella exposure and infection in muskoxen and provides an example of how scientific knowledge and local knowledge can work together to better understand disease status in wildlife. Springer US 2019-08-14 2019 /pmc/articles/PMC6858907/ /pubmed/31414318 http://dx.doi.org/10.1007/s10393-019-01433-3 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Contribution Tomaselli, Matilde Elkin, Brett Kutz, Susan Harms, N. Jane Nymo, H. Ingebjørg Davison, Tracy Leclerc, Lisa-Marie Branigan, Marsha Dumond, Mathieu Tryland, Morten Checkley, Sylvia A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016 |
title | A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016 |
title_full | A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016 |
title_fullStr | A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016 |
title_full_unstemmed | A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016 |
title_short | A Transdisciplinary Approach to Brucella in Muskoxen of the Western Canadian Arctic 1989–2016 |
title_sort | transdisciplinary approach to brucella in muskoxen of the western canadian arctic 1989–2016 |
topic | Original Contribution |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858907/ https://www.ncbi.nlm.nih.gov/pubmed/31414318 http://dx.doi.org/10.1007/s10393-019-01433-3 |
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