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A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition

BACKGROUND: The initiation of lactation challenges the ability of the modern lactating cow to maintain calcium homeostasis, and typically results in a drop in blood calcium levels, leading to mobilization of calcium reserves from skeletal stores. As such, the recommendation to provide supplemental c...

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Autores principales: Shock, Daniel A, Roche, Steven M, Genore, Rachel, Olson, Merle E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859166/
https://www.ncbi.nlm.nih.gov/pubmed/32010605
http://dx.doi.org/10.2147/VMRR.S219740
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author Shock, Daniel A
Roche, Steven M
Genore, Rachel
Olson, Merle E
author_facet Shock, Daniel A
Roche, Steven M
Genore, Rachel
Olson, Merle E
author_sort Shock, Daniel A
collection PubMed
description BACKGROUND: The initiation of lactation challenges the ability of the modern lactating cow to maintain calcium homeostasis, and typically results in a drop in blood calcium levels, leading to mobilization of calcium reserves from skeletal stores. As such, the recommendation to provide supplemental calcium at parturition to older cows has become an industry-standard practice. METHODS: Mature cows were treated at calving and 12 hrs later with either the novel calcium bolus (NB) or a commercially available calcium bolus (CB). Blood was collected from animals at 0, 1, 6, 12, 13, and 24 hrs following calving, and the resulting serum samples were analyzed. RESULTS: Overall, there was no statistical difference between the NB and CB groups for blood calcium levels within the first 24 hrs following parturition (P = 0.50). Cows in both groups experienced a significant increase in serum calcium by 1 hr after parturition; however, this increase was not sustained through subsequent sampling times. CONCLUSION: This pilot study demonstrates that both boluses have a similar effect in the elevation of blood calcium.
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spelling pubmed-68591662020-01-31 A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition Shock, Daniel A Roche, Steven M Genore, Rachel Olson, Merle E Vet Med (Auckl) Original Research BACKGROUND: The initiation of lactation challenges the ability of the modern lactating cow to maintain calcium homeostasis, and typically results in a drop in blood calcium levels, leading to mobilization of calcium reserves from skeletal stores. As such, the recommendation to provide supplemental calcium at parturition to older cows has become an industry-standard practice. METHODS: Mature cows were treated at calving and 12 hrs later with either the novel calcium bolus (NB) or a commercially available calcium bolus (CB). Blood was collected from animals at 0, 1, 6, 12, 13, and 24 hrs following calving, and the resulting serum samples were analyzed. RESULTS: Overall, there was no statistical difference between the NB and CB groups for blood calcium levels within the first 24 hrs following parturition (P = 0.50). Cows in both groups experienced a significant increase in serum calcium by 1 hr after parturition; however, this increase was not sustained through subsequent sampling times. CONCLUSION: This pilot study demonstrates that both boluses have a similar effect in the elevation of blood calcium. Dove 2019-11-13 /pmc/articles/PMC6859166/ /pubmed/32010605 http://dx.doi.org/10.2147/VMRR.S219740 Text en © 2019 Shock et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Shock, Daniel A
Roche, Steven M
Genore, Rachel
Olson, Merle E
A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition
title A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition
title_full A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition
title_fullStr A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition
title_full_unstemmed A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition
title_short A Pilot Study To Evaluate The Effect Of A Novel Calcium And Vitamin D-Containing Oral Bolus On Serum Calcium Levels In Holstein Dairy Cows Following Parturition
title_sort pilot study to evaluate the effect of a novel calcium and vitamin d-containing oral bolus on serum calcium levels in holstein dairy cows following parturition
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859166/
https://www.ncbi.nlm.nih.gov/pubmed/32010605
http://dx.doi.org/10.2147/VMRR.S219740
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