A Novel Aptamer LL4A Specifically Targets Vemurafenib-Resistant Melanoma through Binding to the CD63 Protein

Melanoma is a highly aggressive tumor with a poor prognosis, and half of all melanoma patients harbor BRAF mutations. A BRAF inhibitor, vemurafenib (PLX4032), has been approved by the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) to treat advanced melanoma patients with B...

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Detalles Bibliográficos
Autores principales: Li, Hui, Liu, Juan, Xiao, Xiaojuan, Sun, Shuming, Zhang, Hui, Zhang, Yibin, Zhou, Weihua, Zhang, Bin, Roy, Mridul, Liu, Hong, Ye, Mao, Wang, Zi, Liu-Smith, Feng, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859286/
https://www.ncbi.nlm.nih.gov/pubmed/31726389
http://dx.doi.org/10.1016/j.omtn.2019.10.005

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