TraFo-CRISPR: Enhanced Genome Engineering by Transient Foamy Virus Vector-Mediated Delivery of CRISPR/Cas9 Components

The adaptation of CRISPR/Cas technology for use in mammals has revolutionized genome engineering. In particular with regard to clinical application, efficient expression of Cas9 within a narrow time frame is highly desirable to minimize the accumulation of off-target editing. We developed an effecti...

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Detalles Bibliográficos
Autores principales: Lindel, Fabian, Dodt, Carolin R., Weidner, Niklas, Noll, Monique, Bergemann, Fabian, Behrendt, Rayk, Fischer, Sarah, Dietrich, Josephine, Cartellieri, Marc, Hamann, Martin V., Lindemann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859288/
https://www.ncbi.nlm.nih.gov/pubmed/31726388
http://dx.doi.org/10.1016/j.omtn.2019.10.006

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