Cargando…

Cdc42 Promotes ADSC-Derived IPC Induction, Proliferation, And Insulin Secretion Via Wnt/β-Catenin Signaling

PURPOSE: Type 1 diabetes mellitus (T1DM) is characterized by irreversible islet β cell destruction. Accumulative evidence indicated that Cdc42 and Wnt/β-catenin signaling both play a critical role in the pathogenesis and development of T1DM. Further, bio-molecular mechanisms in adipose-derived mesen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Xing-Hua, Huang, Qi-Yuan, Qian, Xian-Ling, Duan, Jing, Jiao, Xue-Qiao, Wu, Long-Yuan, Huang, Qing-Yun, Li, Jun, Lai, Xing-Ning, Shi, Yu-Bo, Xiong, Li-Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859340/ https://www.ncbi.nlm.nih.gov/pubmed/32009808 http://dx.doi.org/10.2147/DMSO.S226055

Ejemplares similares

Cdc42: A Novel Regulator of Insulin Secretion and Diabetes-Associated Diseases
por: Huang, Qi-Yuan, et al.
Publicado: (2019)

miR-29a Negatively Affects Glucose-Stimulated Insulin Secretion and MIN6 Cell Proliferation via Cdc42/β-Catenin Signaling
por: Duan, Jing, et al.
Publicado: (2019)

Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion
por: Jiang, Shan, et al.
Publicado: (2022)

Focus on Cdc42 in Breast Cancer: New Insights, Target Therapy Development and Non-Coding RNAs
por: Zhang, Yu, et al.
Publicado: (2019)

The Roles of Different Multigene Combinations of Pdx1, Ngn3, Sox9, Pax4, and Nkx2.2 in the Reprogramming of Canine ADSCs Into IPCs
por: Gao, Dengke, et al.
Publicado: (2022)

ADSC-Exos containing MALAT1 promotes wound healing by targeting miR-124 through activating Wnt/β-catenin pathway
por: He, Lin, et al.
Publicado: (2020)

Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity
por: Schlessinger, Karni, et al.
Publicado: (2007)

The Borg family of Cdc42 effector proteins Cdc42EP1–5
por: Farrugia, Aaron J., et al.
Publicado: (2016)

Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts
por: Farrugia, Aaron J., et al.
Publicado: (2016)

IPC – Isoelectric Point Calculator
por: Kozlowski, Lukasz P.
Publicado: (2016)

Measuring interdisciplinarity in clinical practice with IPC59, a modified and improved version of IPC65
por: Poder, Thomas G., et al.
Publicado: (2018)

Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development
por: Ma, Yuanyuan, et al.
Publicado: (2021)

Cdc42 turns the spindle
por: Leslie, Mitch
Publicado: (2008)

The first buds of Cdc42
por: Short, Ben
Publicado: (2015)

Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation
por: Kho, Mary, et al.
Publicado: (2019)

Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis
por: Duan, Xin, et al.
Publicado: (2021)

CDC42-mediated Wnt signaling facilitates odontogenic differentiation of DPCs during tooth root elongation
por: Zhou, Tao, et al.
Publicado: (2023)

Rational Targeting of Cdc42 Overcomes Drug Resistance of Multiple Myeloma
por: Nguyen, Phuong, et al.
Publicado: (2019)

The Cdc42 effectors Gic1 and Gic2 regulate polarized post-Golgi secretion
por: Liu, Ying, et al.
Publicado: (2019)

WNT4 secreted by tumor tissues promotes tumor progression in colorectal cancer by activation of the Wnt/β-catenin signalling pathway
por: Yang, Dongmei, et al.
Publicado: (2020)

Regulation and functional significance of CDC42 alternative splicing in ovarian cancer
por: He, Xiaolong, et al.
Publicado: (2015)

Assessment of Infection Prevention and Control (IPC) Implementation and Strategies Used for IPC Preparedness at Facility Level in Underdeveloped Areas of Pakistan
por: Tahir, Majid Ali, et al.
Publicado: (2023)

The Cdc42 GAP Rga6 promotes monopolar outgrowth of spores
por: Wei, Wenfan, et al.
Publicado: (2022)

Regulating Cdc42 and Its Signaling Pathways in Cancer: Small Molecules and MicroRNA as New Treatment Candidates
por: Xiao, Xing-Hua, et al.
Publicado: (2018)

CDC42—A promising immune-related target in glioma
por: Jiang, Tao, et al.
Publicado: (2023)

YC-1 Antagonizes Wnt/β-Catenin Signaling Through the EBP1 p42 Isoform in Hepatocellular Carcinoma
por: Wu, Ju-Yun, et al.
Publicado: (2019)

Opening the Floor to PLCs and IPCs: CODESYS in UNICOS
por: Rochez, J, et al.
Publicado: (2014)

Challenges in IPC training for non–healthcare workers
por: Abdul Majid, Faridah Binte, et al.
Publicado: (2022)

A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells
por: Tiwari, Rajiv L., et al.
Publicado: (2021)

Spatial analysis of Cdc42 activity reveals a role for plasma membrane–associated Cdc42 in centrosome regulation
por: Herrington, Kari A., et al.
Publicado: (2017)

CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling
por: Meng, Dong-Fang, et al.
Publicado: (2017)

ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42
por: Zhang, Xin, et al.
Publicado: (2022)

Mechanism of Cdc42-induced Actin Polymerization in Neutrophil Extracts
por: Zigmond, Sally H., et al.
Publicado: (1998)

Advances in the study of CDC42 in the female reproductive system
por: Mei, Qiaojuan, et al.
Publicado: (2021)

Application of ADSCs and their Exosomes in Scar Prevention
por: Li, Cong, et al.
Publicado: (2021)

Profilin Enhances Cdc42-Induced Nucleation of Actin Polymerization
por: Yang, Changsong, et al.
Publicado: (2000)

Nucleocytoplasmic Shuttling of the Cdc42p Exchange Factor Cdc24p
por: Nern, Aljoscha, et al.
Publicado: (2000)

Wnt/β-catenin activation and macrophage induction during liver cancer development following steatosis
por: Debebe, A, et al.
Publicado: (2017)

A Role for Cdc42 in Macrophage Chemotaxis
por: Allen, William E., et al.
Publicado: (1998)

Cdc42 and Tinman march to the same beat
por: Short, Ben
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_m3n6oqgdq04lf829e34kopb1bj