Pneumonitis Due to Oren-gedoku-to (Coptis Detoxifying Decoction)

A 54-year-old man started to take oren-gedoku-to (coptis detoxifying decoction) because he was experiencing chronic hot flashes, night sweats and insomnia. He developed a high fever from the day of intake. At day 17, he stopped taking oren-gedoku-to because of malaise and chills, and he was admitted...

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Detalles Bibliográficos
Autores principales: Mochizuki, Naoto, Ano, Satoshi, Kikuchi, Norihiro, Sakai, Chio, Masuda, Michiko, Kondo, Yuzuru, Ishii, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859392/
https://www.ncbi.nlm.nih.gov/pubmed/31611510
http://dx.doi.org/10.2169/internalmedicine.2586-18
Descripción
Sumario:A 54-year-old man started to take oren-gedoku-to (coptis detoxifying decoction) because he was experiencing chronic hot flashes, night sweats and insomnia. He developed a high fever from the day of intake. At day 17, he stopped taking oren-gedoku-to because of malaise and chills, and he was admitted to our hospital. Drug-induced pneumonitis was suspected, and all drugs were stopped. Consequently, his symptoms, laboratory data and chest X-ray findings markedly improved. The results of a lymphocyte stimulation test were positive for oren-gedoku-to and one of its components, ougon (Baikal skullcap). Based on these findings, we diagnosed him with pneumonitis caused by ougon.

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