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Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis
A 45-year-old man was admitted with acute abdominal pain and eosinophilia. Abdominal computed tomography revealed thickness of the ascending and transverse colon with decreased contrast enhancement and a small amount of ascites. In an emergency operation, the necrotic colon was resected. Histopathol...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859400/ https://www.ncbi.nlm.nih.gov/pubmed/31243218 http://dx.doi.org/10.2169/internalmedicine.2802-19 |
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author | Oiwa, Hiroshi Taniguchi, Kohei Miyoshi, Natsuki Sasaki, Keiko Ichimura, Kouichi Kubota, Tetsushi Sato, Daisuke |
author_facet | Oiwa, Hiroshi Taniguchi, Kohei Miyoshi, Natsuki Sasaki, Keiko Ichimura, Kouichi Kubota, Tetsushi Sato, Daisuke |
author_sort | Oiwa, Hiroshi |
collection | PubMed |
description | A 45-year-old man was admitted with acute abdominal pain and eosinophilia. Abdominal computed tomography revealed thickness of the ascending and transverse colon with decreased contrast enhancement and a small amount of ascites. In an emergency operation, the necrotic colon was resected. Histopathology showed subserous medium-sized arteritis with abundant eosinophil infiltrates and thrombosis in the portal vein branches. He was diagnosed with polyarteritis nodosa (PAN), and immunosuppressive therapy improved his condition. Two years later, the disease recurred with ischemic cutaneous lesions and marked eosinophilia. Our experience suggests that marked eosinophilia in PAN may imply severe organ involvement, including gastrointestinal necrosis, as well as the association of venous thrombosis. |
format | Online Article Text |
id | pubmed-6859400 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-68594002019-11-21 Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis Oiwa, Hiroshi Taniguchi, Kohei Miyoshi, Natsuki Sasaki, Keiko Ichimura, Kouichi Kubota, Tetsushi Sato, Daisuke Intern Med Case Report A 45-year-old man was admitted with acute abdominal pain and eosinophilia. Abdominal computed tomography revealed thickness of the ascending and transverse colon with decreased contrast enhancement and a small amount of ascites. In an emergency operation, the necrotic colon was resected. Histopathology showed subserous medium-sized arteritis with abundant eosinophil infiltrates and thrombosis in the portal vein branches. He was diagnosed with polyarteritis nodosa (PAN), and immunosuppressive therapy improved his condition. Two years later, the disease recurred with ischemic cutaneous lesions and marked eosinophilia. Our experience suggests that marked eosinophilia in PAN may imply severe organ involvement, including gastrointestinal necrosis, as well as the association of venous thrombosis. The Japanese Society of Internal Medicine 2019-06-27 2019-10-15 /pmc/articles/PMC6859400/ /pubmed/31243218 http://dx.doi.org/10.2169/internalmedicine.2802-19 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Oiwa, Hiroshi Taniguchi, Kohei Miyoshi, Natsuki Sasaki, Keiko Ichimura, Kouichi Kubota, Tetsushi Sato, Daisuke Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis |
title | Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis |
title_full | Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis |
title_fullStr | Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis |
title_full_unstemmed | Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis |
title_short | Polyarteritis Nodosa with Marked Eosinophilia, Associated with Severe Gastrointestinal Tract Involvement and Recurrent Venous Thrombosis |
title_sort | polyarteritis nodosa with marked eosinophilia, associated with severe gastrointestinal tract involvement and recurrent venous thrombosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859400/ https://www.ncbi.nlm.nih.gov/pubmed/31243218 http://dx.doi.org/10.2169/internalmedicine.2802-19 |
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