Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells conserved across mammalian species, including mice and humans. By sequencing RNA from sorted MR1-5-OP-RU tetramer(+) cells derived from either human blood or murine lungs, we define the basic transcriptome of an activ...

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Detalles Bibliográficos
Autores principales: Hinks, Timothy S.C., Marchi, Emanuele, Jabeen, Maisha, Olshansky, Moshe, Kurioka, Ayako, Pediongco, Troi J., Meehan, Bronwyn S., Kostenko, Lyudmila, Turner, Stephen J., Corbett, Alexandra J., Chen, Zhenjun, Klenerman, Paul, McCluskey, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859474/
https://www.ncbi.nlm.nih.gov/pubmed/31533045
http://dx.doi.org/10.1016/j.celrep.2019.07.039

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