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Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring

In patients with atrial fibrillation (AF), the prevalence of moderate-to-severe sleep-disordered breathing (SDB) ranges between 21% and 72% and observational studies have demonstrated that SDB reduces the efficacy of rhythm control strategies, while treatment with continuous positive airway pressure...

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Autores principales: Linz, Dominik, Baumert, Mathias, Desteghe, Lien, Kadhim, Kadhim, Vernooy, Kevin, Kalman, Jonathan M., Dobrev, Dobromir, Arzt, Michael, Sastry, Manu, Crijns, Harry J.G.M., Schotten, Ulrich, Cowie, Martin R., McEvoy, R. Doug, Heidbuchel, Hein, Hendriks, Jeroen, Sanders, Prashanthan, Lau, Dennis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859526/
https://www.ncbi.nlm.nih.gov/pubmed/31763438
http://dx.doi.org/10.1016/j.ijcha.2019.100424
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author Linz, Dominik
Baumert, Mathias
Desteghe, Lien
Kadhim, Kadhim
Vernooy, Kevin
Kalman, Jonathan M.
Dobrev, Dobromir
Arzt, Michael
Sastry, Manu
Crijns, Harry J.G.M.
Schotten, Ulrich
Cowie, Martin R.
McEvoy, R. Doug
Heidbuchel, Hein
Hendriks, Jeroen
Sanders, Prashanthan
Lau, Dennis H.
author_facet Linz, Dominik
Baumert, Mathias
Desteghe, Lien
Kadhim, Kadhim
Vernooy, Kevin
Kalman, Jonathan M.
Dobrev, Dobromir
Arzt, Michael
Sastry, Manu
Crijns, Harry J.G.M.
Schotten, Ulrich
Cowie, Martin R.
McEvoy, R. Doug
Heidbuchel, Hein
Hendriks, Jeroen
Sanders, Prashanthan
Lau, Dennis H.
author_sort Linz, Dominik
collection PubMed
description In patients with atrial fibrillation (AF), the prevalence of moderate-to-severe sleep-disordered breathing (SDB) ranges between 21% and 72% and observational studies have demonstrated that SDB reduces the efficacy of rhythm control strategies, while treatment with continuous positive airway pressure lowers the rate of AF recurrence. Currently, the number of apneas and hypopneas per hour (apnea-hypopnea-index, AHI) determined during a single overnight sleep study is clinically used to assess the severity of SDB. However, recent studies suggest that SDB-severity in an individual patient is not stable over time but exhibits a considerable night-to-night variability which cannot be detected by only one overnight sleep assessment. Nightly SDB-severity assessment rather than the single-night diagnosis by one overnight sleep study may better reflect the exposure to SDB-related factors and yield a superior metric to determine SDB-severity in the management of AF. In this review we discuss mechanisms of night-to-night SDB variability, arrhythmogenic consequences of night-to-night SDB variability, strategies for longitudinal assessment of nightly SDB-severity and clinical implications for screening and management of SDB in AF patients.
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spelling pubmed-68595262019-11-22 Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring Linz, Dominik Baumert, Mathias Desteghe, Lien Kadhim, Kadhim Vernooy, Kevin Kalman, Jonathan M. Dobrev, Dobromir Arzt, Michael Sastry, Manu Crijns, Harry J.G.M. Schotten, Ulrich Cowie, Martin R. McEvoy, R. Doug Heidbuchel, Hein Hendriks, Jeroen Sanders, Prashanthan Lau, Dennis H. Int J Cardiol Heart Vasc Review In patients with atrial fibrillation (AF), the prevalence of moderate-to-severe sleep-disordered breathing (SDB) ranges between 21% and 72% and observational studies have demonstrated that SDB reduces the efficacy of rhythm control strategies, while treatment with continuous positive airway pressure lowers the rate of AF recurrence. Currently, the number of apneas and hypopneas per hour (apnea-hypopnea-index, AHI) determined during a single overnight sleep study is clinically used to assess the severity of SDB. However, recent studies suggest that SDB-severity in an individual patient is not stable over time but exhibits a considerable night-to-night variability which cannot be detected by only one overnight sleep assessment. Nightly SDB-severity assessment rather than the single-night diagnosis by one overnight sleep study may better reflect the exposure to SDB-related factors and yield a superior metric to determine SDB-severity in the management of AF. In this review we discuss mechanisms of night-to-night SDB variability, arrhythmogenic consequences of night-to-night SDB variability, strategies for longitudinal assessment of nightly SDB-severity and clinical implications for screening and management of SDB in AF patients. Elsevier 2019-10-18 /pmc/articles/PMC6859526/ /pubmed/31763438 http://dx.doi.org/10.1016/j.ijcha.2019.100424 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Linz, Dominik
Baumert, Mathias
Desteghe, Lien
Kadhim, Kadhim
Vernooy, Kevin
Kalman, Jonathan M.
Dobrev, Dobromir
Arzt, Michael
Sastry, Manu
Crijns, Harry J.G.M.
Schotten, Ulrich
Cowie, Martin R.
McEvoy, R. Doug
Heidbuchel, Hein
Hendriks, Jeroen
Sanders, Prashanthan
Lau, Dennis H.
Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring
title Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring
title_full Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring
title_fullStr Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring
title_full_unstemmed Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring
title_short Nightly sleep apnea severity in patients with atrial fibrillation: Potential applications of long-term sleep apnea monitoring
title_sort nightly sleep apnea severity in patients with atrial fibrillation: potential applications of long-term sleep apnea monitoring
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859526/
https://www.ncbi.nlm.nih.gov/pubmed/31763438
http://dx.doi.org/10.1016/j.ijcha.2019.100424
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