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ROS and the DNA damage response in cancer
Reactive oxygen species (ROS) are a group of short-lived, highly reactive, oxygen-containing molecules that can induce DNA damage and affect the DNA damage response (DDR). There is unequivocal pre-clinical and clinical evidence that ROS influence the genotoxic stress caused by chemotherapeutics agen...
Autores principales: | Srinivas, Upadhyayula Sai, Tan, Bryce W.Q., Vellayappan, Balamurugan A., Jeyasekharan, Anand D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859528/ https://www.ncbi.nlm.nih.gov/pubmed/30612957 http://dx.doi.org/10.1016/j.redox.2018.101084 |
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