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Advanced oxidation protein products induce G1 phase arrest in intestinal epithelial cells via a RAGE/CD36-JNK-p27kip1 mediated pathway

Intestinal epithelial cell (IEC) cycle arrest has recently been found to be involved in the pathogenesis of Crohn's disease (CD). However, the mechanism underlying the regulation of this form of cell cycle arrest, remains unclear. Here, we investigated the roles that advanced oxidation protein...

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Detalles Bibliográficos
Autores principales: Shi, Jie, Sun, Shibo, Liao, Yan, Tang, Jing, Xu, Xiaoping, Qin, Biyan, Qin, Caolitao, Peng, Lishan, Luo, Mengshi, Bai, Lan, Xie, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859530/
https://www.ncbi.nlm.nih.gov/pubmed/31014575
http://dx.doi.org/10.1016/j.redox.2019.101196

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