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NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis
The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is a key regulator of the cellular antioxidant response, controlling the expression of genes that counteract oxidative and electrophilic stresses. Many pathological conditions are linked to imbalances in redox homeostasis, i...
Autores principales: | Dodson, Matthew, Castro-Portuguez, Raul, Zhang, Donna D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859567/ https://www.ncbi.nlm.nih.gov/pubmed/30692038 http://dx.doi.org/10.1016/j.redox.2019.101107 |
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