Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes

While the role of mitochondrial metabolism in controlling T-lymphocyte activation and function is becoming more clear, the specifics of how mitochondrial redox signaling contributes to T-lymphocyte regulation remains elusive. Here, we examined the global effects of elevated mitochondrial superoxide...

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Detalles Bibliográficos
Autores principales: Moshfegh, C.M., Collins, C.W., Gunda, V., Vasanthakumar, A., Cao, J.Z., Singh, P.K., Godley, L.A., Case, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859572/
https://www.ncbi.nlm.nih.gov/pubmed/30819616
http://dx.doi.org/10.1016/j.redox.2019.101141

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