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gRASping the redox lever to modulate cancer cell fate signaling

RAS proteins are critical regulators of signaling networks controlling diverse cellular functions such as cell proliferation and survival and its mutation are among the most powerful oncogenic drivers in human cancers. Despite intense efforts, direct RAS-targeting strategies remain elusive due to it...

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Detalles Bibliográficos
Autores principales: Foo, Chuan Han Jonathan, Pervaiz, Shazib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859584/
https://www.ncbi.nlm.nih.gov/pubmed/30638892
http://dx.doi.org/10.1016/j.redox.2018.101094