Discovery of bioactive nitrated lipids and nitro-lipid-protein adducts using mass spectrometry-based approaches

Nitro-fatty acids (NO(2)-FA) undergo reversible Michael adduction reactions with cysteine and histidine residues leading to the post-translational modification (PTM) of proteins. This electrophilic character of NO(2)-FA is strictly related to their biological roles. The NO(2)-FA-induced PTM of signa...

Descripción completa

Detalles Bibliográficos
Autores principales: Melo, Tânia, Montero-Bullón, Javier-Fernando, Domingues, Pedro, Domingues, M. Rosário
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Lipoxidation in pathophysiology and its assessment by high precision methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859590/
https://www.ncbi.nlm.nih.gov/pubmed/30718106
http://dx.doi.org/10.1016/j.redox.2019.101106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859590/
https://www.ncbi.nlm.nih.gov/pubmed/30718106
http://dx.doi.org/10.1016/j.redox.2019.101106

Ejemplares similares