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Discovery of bioactive nitrated lipids and nitro-lipid-protein adducts using mass spectrometry-based approaches

Nitro-fatty acids (NO(2)-FA) undergo reversible Michael adduction reactions with cysteine and histidine residues leading to the post-translational modification (PTM) of proteins. This electrophilic character of NO(2)-FA is strictly related to their biological roles. The NO(2)-FA-induced PTM of signa...

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Detalles Bibliográficos
Autores principales:	Melo, Tânia, Montero-Bullón, Javier-Fernando, Domingues, Pedro, Domingues, M. Rosário
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Lipoxidation in pathophysiology and its assessment by high precision methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859590/ https://www.ncbi.nlm.nih.gov/pubmed/30718106 http://dx.doi.org/10.1016/j.redox.2019.101106

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