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Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty
This study aimed to evaluate whether adding a vacuum erection device (VED) to regular use of Tadalafil could achieve better penile rehabilitation following posterior urethroplasty for pelvic fracture-related urethral injury (PFUI). Altogether, 78 PFUI patients with erectile dysfunction (ED) after pr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859665/ https://www.ncbi.nlm.nih.gov/pubmed/31169141 http://dx.doi.org/10.4103/aja.aja_50_19; |
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author | Zhang, Dong-Liang Chen, Zhong Wang, Fei-Xiang Zhang, Jiong Xie, Hong Wang, Ze-Yu Gu, Yu-Bo Fu, Qiang Song, Lu-Jie |
author_facet | Zhang, Dong-Liang Chen, Zhong Wang, Fei-Xiang Zhang, Jiong Xie, Hong Wang, Ze-Yu Gu, Yu-Bo Fu, Qiang Song, Lu-Jie |
author_sort | Zhang, Dong-Liang |
collection | PubMed |
description | This study aimed to evaluate whether adding a vacuum erection device (VED) to regular use of Tadalafil could achieve better penile rehabilitation following posterior urethroplasty for pelvic fracture-related urethral injury (PFUI). Altogether, 78 PFUI patients with erectile dysfunction (ED) after primary posterior urethroplasty were enrolled and divided into two treatment groups: VED combined with Tadalafil (Group 1, n = 36) and Tadalafil only (Group 2, n = 42). Changes in penile length, testosterone level, International Index of Erectile Function-5 (IIEF-5) questionnaire, Quality of Erection Questionnaire (QEQ), and nocturnal penile tumescence (NPT) testing were used to assess erectile function before and after 6 months of ED treatment. Results showed that the addition of VED to regular use of Tadalafil preserved more penile length statistically (0.4 ± 0.9 vs −0.8 ± 0.7 cm, P < 0.01). IIEF-5 score and QEQ score in Group 1 were higher than Group 2 (both P < 0.05). After treatment, 21/36 (58.3%) Group 1 patients and 19/42 (45.2%) Group 2 patients could complete vaginal penetration. Group 1 patients also had markedly improved testosterone levels (P = 0.01). Unexpectedly, there was no significant difference in NPT testing between two therapies. For PFUI patients with ED after posterior urethroplasty, the addition of VED to regular use of Tadalafil could significantly improve their conditions – improving erection and increasing penile length – thus increasing patient satisfaction and confidence in penile rehabilitation. |
format | Online Article Text |
id | pubmed-6859665 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-68596652019-12-05 Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty Zhang, Dong-Liang Chen, Zhong Wang, Fei-Xiang Zhang, Jiong Xie, Hong Wang, Ze-Yu Gu, Yu-Bo Fu, Qiang Song, Lu-Jie Asian J Androl Original Article This study aimed to evaluate whether adding a vacuum erection device (VED) to regular use of Tadalafil could achieve better penile rehabilitation following posterior urethroplasty for pelvic fracture-related urethral injury (PFUI). Altogether, 78 PFUI patients with erectile dysfunction (ED) after primary posterior urethroplasty were enrolled and divided into two treatment groups: VED combined with Tadalafil (Group 1, n = 36) and Tadalafil only (Group 2, n = 42). Changes in penile length, testosterone level, International Index of Erectile Function-5 (IIEF-5) questionnaire, Quality of Erection Questionnaire (QEQ), and nocturnal penile tumescence (NPT) testing were used to assess erectile function before and after 6 months of ED treatment. Results showed that the addition of VED to regular use of Tadalafil preserved more penile length statistically (0.4 ± 0.9 vs −0.8 ± 0.7 cm, P < 0.01). IIEF-5 score and QEQ score in Group 1 were higher than Group 2 (both P < 0.05). After treatment, 21/36 (58.3%) Group 1 patients and 19/42 (45.2%) Group 2 patients could complete vaginal penetration. Group 1 patients also had markedly improved testosterone levels (P = 0.01). Unexpectedly, there was no significant difference in NPT testing between two therapies. For PFUI patients with ED after posterior urethroplasty, the addition of VED to regular use of Tadalafil could significantly improve their conditions – improving erection and increasing penile length – thus increasing patient satisfaction and confidence in penile rehabilitation. Wolters Kluwer - Medknow 2019-06-04 /pmc/articles/PMC6859665/ /pubmed/31169141 http://dx.doi.org/10.4103/aja.aja_50_19; Text en Copyright: © The Author(s)(2019) http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Zhang, Dong-Liang Chen, Zhong Wang, Fei-Xiang Zhang, Jiong Xie, Hong Wang, Ze-Yu Gu, Yu-Bo Fu, Qiang Song, Lu-Jie Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty |
title | Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty |
title_full | Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty |
title_fullStr | Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty |
title_full_unstemmed | Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty |
title_short | Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty |
title_sort | adding a vacuum erection device to regular use of tadalafil improves penile rehabilitation after posterior urethroplasty |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859665/ https://www.ncbi.nlm.nih.gov/pubmed/31169141 http://dx.doi.org/10.4103/aja.aja_50_19; |
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