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Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients

INTRODUCTION: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India where...

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Autores principales: Monga, Seema, Malik, Junaid, Sharma, Arun Parkash, Jan, Sabeena, Nabi, Nighat, Bahadur, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859672/
https://www.ncbi.nlm.nih.gov/pubmed/31798306
http://dx.doi.org/10.1177/1179550619888856
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author Monga, Seema
Malik, Junaid
Sharma, Arun Parkash
Jan, Sabeena
Nabi, Nighat
Bahadur, Sudhir
author_facet Monga, Seema
Malik, Junaid
Sharma, Arun Parkash
Jan, Sabeena
Nabi, Nighat
Bahadur, Sudhir
author_sort Monga, Seema
collection PubMed
description INTRODUCTION: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India wherein we identify among allergic rhinitis patients who despite not having overt asthmatic symptoms, have pulmonary function derangements, quite possibly at a subclinical disease level. MATERIALS AND METHODS: We studied 74 patients of allergic rhinitis and after meticulous clinical work up, they underwent blood tests including hemogram, absolute eosinophil count, and total serum IgE followed by pulmonary function tests. RESULTS: Out of 74 patients 60 (81%) had intermittent allergic rhinitis whereas only 14 (19%) had persistent allergic rhinitis. Pulmonary function tests showed reversible obstruction, ie, >10% improvement in FEV(1) with inhaled bronchodilators (as seen in asthma) in 18 (24.3%), mild obstruction in 14, and moderate obstruction in 4 cases. CONCLUSION: The study emphasizes the importance of pulmonary symptoms and the performance of pulmonary function tests in cases of allergic rhinitis patients to rule out latent asthma.
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spelling pubmed-68596722019-12-03 Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients Monga, Seema Malik, Junaid Sharma, Arun Parkash Jan, Sabeena Nabi, Nighat Bahadur, Sudhir Clin Med Insights Ear Nose Throat Original Research INTRODUCTION: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India wherein we identify among allergic rhinitis patients who despite not having overt asthmatic symptoms, have pulmonary function derangements, quite possibly at a subclinical disease level. MATERIALS AND METHODS: We studied 74 patients of allergic rhinitis and after meticulous clinical work up, they underwent blood tests including hemogram, absolute eosinophil count, and total serum IgE followed by pulmonary function tests. RESULTS: Out of 74 patients 60 (81%) had intermittent allergic rhinitis whereas only 14 (19%) had persistent allergic rhinitis. Pulmonary function tests showed reversible obstruction, ie, >10% improvement in FEV(1) with inhaled bronchodilators (as seen in asthma) in 18 (24.3%), mild obstruction in 14, and moderate obstruction in 4 cases. CONCLUSION: The study emphasizes the importance of pulmonary symptoms and the performance of pulmonary function tests in cases of allergic rhinitis patients to rule out latent asthma. SAGE Publications 2019-11-15 /pmc/articles/PMC6859672/ /pubmed/31798306 http://dx.doi.org/10.1177/1179550619888856 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Monga, Seema
Malik, Junaid
Sharma, Arun Parkash
Jan, Sabeena
Nabi, Nighat
Bahadur, Sudhir
Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients
title Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients
title_full Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients
title_fullStr Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients
title_full_unstemmed Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients
title_short Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients
title_sort deranged pulmonary function tests in allergic rhinitis in north indian patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859672/
https://www.ncbi.nlm.nih.gov/pubmed/31798306
http://dx.doi.org/10.1177/1179550619888856
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