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Insights into evolutionary interaction patterns of the 'Phosphorylation Activation Segment' in kinase

We are interested in studying the phosphorylation of the kinase activation loop, distinguishing the passage from the unphosphorylated to the phosphorylated form without allostery. We performed an interaction study to trace the change of interactions between the activation segment and the kinase cata...

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Detalles Bibliográficos
Autores principales: Ahiri, Adil, Garmes, Hocine, Podlipnik, Crtomir, Aboulmouhajir, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859708/
https://www.ncbi.nlm.nih.gov/pubmed/31787816
http://dx.doi.org/10.6026/97320630015666