Cargando…
Cryptotanshinone Attenuates Airway Remodeling by Inhibiting Crosstalk Between Tumor Necrosis Factor-Like Weak Inducer of Apoptosis and Transforming Growth Factor Beta 1 Signaling Pathways in Asthma
The study is to investigate the effect of cryptotanshinone (CTS) on airway remodeling and the possible mechanism. Male BALB/c mice were pretreated with CTS or dexamethasone 30 min before nebulized inhalation of ovalbumin (OVA). CTS significantly inhibited OVA-induced increases of eosinophils and neu...
Autores principales: | Wang, Chongyang, Zheng, Mingyu, Choi, Yunho, Jiang, Jingzhi, Li, Li, Li, Junfeng, Xu, Chang, Xian, Zhemin, Li, Yan, Piao, Hongmei, Li, Liangchang, Yan, Guanghai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859802/ https://www.ncbi.nlm.nih.gov/pubmed/31780948 http://dx.doi.org/10.3389/fphar.2019.01338 |
Ejemplares similares
-
Recombinant Pyrin Domain Protein Attenuates Airway Inflammation and Alleviates Epithelial-Mesenchymal Transition by Inhibiting Crosstalk Between TGFβ1 and Notch1 Signaling in Chronic Asthmatic Mice
por: Wang, Zhiguang, et al.
Publicado: (2020) -
Imperatorin Suppresses Anaphylactic Reaction and IgE-Mediated Allergic Responses by Inhibiting Multiple Steps of FceRI Signaling in Mast Cells: IMP Alleviates Allergic Responses in PCA
por: Xian, Zhemin, et al.
Publicado: (2019) -
DEK‐targeting aptamer DTA‐64 attenuates bronchial EMT‐mediated airway remodelling by suppressing TGF‐β1/Smad, MAPK and PI3K signalling pathway in asthma
por: Song, Yilan, et al.
Publicado: (2020) -
Glaucocalyxin A Attenuates Allergic Responses by Inhibiting Mast Cell Degranulation through p38MAPK/NrF2/HO-1 and HMGB1/TLR4/NF-κB Signaling Pathways
por: Piao, Yihua, et al.
Publicado: (2021) -
MicroRNA-182-5p Attenuates Asthmatic Airway Inflammation by Targeting NOX4
por: Wang, Zhiguang, et al.
Publicado: (2022)