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PMBD: a Comprehensive Plastics Microbial Biodegradation Database

Since the invention over a hundred years ago, plastics have been used in many applications, and they are involved in every aspect of our lives. The extensive usage of plastics results in a tremendous amount of waste, which has become a severe burden on the environment. Several degradation approaches...

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Detalles Bibliográficos
Autores principales: Gan, Zhiqiang, Zhang, Houjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859810/
https://www.ncbi.nlm.nih.gov/pubmed/31738435
http://dx.doi.org/10.1093/database/baz119
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author Gan, Zhiqiang
Zhang, Houjin
author_facet Gan, Zhiqiang
Zhang, Houjin
author_sort Gan, Zhiqiang
collection PubMed
description Since the invention over a hundred years ago, plastics have been used in many applications, and they are involved in every aspect of our lives. The extensive usage of plastics results in a tremendous amount of waste, which has become a severe burden on the environment. Several degradation approaches exist in nature to cope with ever-increasing plastic waste. Among these approaches, biodegradation by microorganisms has emerged as a natural way, which is favored by many environmentally conscious societies. To facilitate the study on biodegradation of plastics, we developed an online resource, Plastics Microbial Biodegradation Database (PMBD), to gather and present the information about microbial biodegradation of plastics. In this database, 949 microorganisms–plastics relationships and 79 genes involved in the biodegradation of plastics were manually collected and confirmed through literature searching. In addition, more than 8000 automatically annotated enzyme sequences, which were predicted to be involved in the plastics biodegradation, were extracted from the TrEMBL section of the UniProt database. The PMBD database is presented with a website at http://pmbd.genome-mining.cn/home. Data may be accessed through browsing or searching. Also included on the website are a sequence alignment tool and a function prediction tool.
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spelling pubmed-68598102019-11-21 PMBD: a Comprehensive Plastics Microbial Biodegradation Database Gan, Zhiqiang Zhang, Houjin Database (Oxford) Original Article Since the invention over a hundred years ago, plastics have been used in many applications, and they are involved in every aspect of our lives. The extensive usage of plastics results in a tremendous amount of waste, which has become a severe burden on the environment. Several degradation approaches exist in nature to cope with ever-increasing plastic waste. Among these approaches, biodegradation by microorganisms has emerged as a natural way, which is favored by many environmentally conscious societies. To facilitate the study on biodegradation of plastics, we developed an online resource, Plastics Microbial Biodegradation Database (PMBD), to gather and present the information about microbial biodegradation of plastics. In this database, 949 microorganisms–plastics relationships and 79 genes involved in the biodegradation of plastics were manually collected and confirmed through literature searching. In addition, more than 8000 automatically annotated enzyme sequences, which were predicted to be involved in the plastics biodegradation, were extracted from the TrEMBL section of the UniProt database. The PMBD database is presented with a website at http://pmbd.genome-mining.cn/home. Data may be accessed through browsing or searching. Also included on the website are a sequence alignment tool and a function prediction tool. Oxford University Press 2019-11-18 /pmc/articles/PMC6859810/ /pubmed/31738435 http://dx.doi.org/10.1093/database/baz119 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Gan, Zhiqiang
Zhang, Houjin
PMBD: a Comprehensive Plastics Microbial Biodegradation Database
title PMBD: a Comprehensive Plastics Microbial Biodegradation Database
title_full PMBD: a Comprehensive Plastics Microbial Biodegradation Database
title_fullStr PMBD: a Comprehensive Plastics Microbial Biodegradation Database
title_full_unstemmed PMBD: a Comprehensive Plastics Microbial Biodegradation Database
title_short PMBD: a Comprehensive Plastics Microbial Biodegradation Database
title_sort pmbd: a comprehensive plastics microbial biodegradation database
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859810/
https://www.ncbi.nlm.nih.gov/pubmed/31738435
http://dx.doi.org/10.1093/database/baz119
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