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Siglec-G Deficiency Ameliorates Hyper-Inflammation and Immune Collapse in Sepsis via Regulating Src Activation

Hyper-inflammation during acute phase and sequential hypo-inflammation during immunosuppressive phase in macrophages/monocytes lead to multiorgan failure syndrome and immune collapse of sepsis, in which toll-like receptor (TLR)-triggered inflammatory responses play a major role. Here, we reported th...

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Detalles Bibliográficos
Autores principales: Li, Wenqian, Li, Yinjiao, Qin, Kewei, Du, Boxiang, Li, Tianliang, Yuan, Hongbin, Han, Chaofeng, Luo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859834/
https://www.ncbi.nlm.nih.gov/pubmed/31781099
http://dx.doi.org/10.3389/fimmu.2019.02575