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Siglec-G Deficiency Ameliorates Hyper-Inflammation and Immune Collapse in Sepsis via Regulating Src Activation
Hyper-inflammation during acute phase and sequential hypo-inflammation during immunosuppressive phase in macrophages/monocytes lead to multiorgan failure syndrome and immune collapse of sepsis, in which toll-like receptor (TLR)-triggered inflammatory responses play a major role. Here, we reported th...
Autores principales: | Li, Wenqian, Li, Yinjiao, Qin, Kewei, Du, Boxiang, Li, Tianliang, Yuan, Hongbin, Han, Chaofeng, Luo, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859834/ https://www.ncbi.nlm.nih.gov/pubmed/31781099 http://dx.doi.org/10.3389/fimmu.2019.02575 |
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