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Biophysical characterizations of the recognition of the AAUAAA polyadenylation signal

Most eukaryotic messenger RNA precursors must undergo 3′-end cleavage and polyadenylation for maturation. We and others recently reported the structure of the AAUAAA polyadenylation signal (PAS) in complex with the protein factors CPSF-30, WDR33, and CPSF-160, revealing the molecular mechanism for t...

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Detalles Bibliográficos
Autores principales: Hamilton, Keith, Sun, Yadong, Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859858/
https://www.ncbi.nlm.nih.gov/pubmed/31462423
http://dx.doi.org/10.1261/rna.070870.119