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Thermodynamic examination of pH and magnesium effect on U6 RNA internal loop
U6 RNA contains a 1 × 2-nt internal loop that folds and unfold during spliceosomal assembly and activation. The 1 × 2 loop consists of a C(67)•A(79) base pair that forms an additional hydrogen bond upon protonation, C(67)•A(+)(79), and uracil (U80) that coordinates the catalytically essential magnes...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859860/ https://www.ncbi.nlm.nih.gov/pubmed/31548339 http://dx.doi.org/10.1261/rna.070466.119 |