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Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus
The efficiency of natural and artificial selection is critically dependent on the recombination rate. However, interbreed and individual variation in recombination rate in poultry remains unknown. Conventional methods of analysis of recombination such as genetic linkage analysis, sperm genotyping an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Copernicus GmbH
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859913/ https://www.ncbi.nlm.nih.gov/pubmed/31807651 http://dx.doi.org/10.5194/aab-62-403-2019 |
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author | Malinovskaya, Lyubov P. Tishakova, Katerina V. Volkova, Natalia A. Torgasheva, Anna A. Tsepilov, Yakov A. Borodin, Pavel M. |
author_facet | Malinovskaya, Lyubov P. Tishakova, Katerina V. Volkova, Natalia A. Torgasheva, Anna A. Tsepilov, Yakov A. Borodin, Pavel M. |
author_sort | Malinovskaya, Lyubov P. |
collection | PubMed |
description | The efficiency of natural and artificial selection is critically dependent on the recombination rate. However, interbreed and individual variation in recombination rate in poultry remains unknown. Conventional methods of analysis of recombination such as genetic linkage analysis, sperm genotyping and chiasma count at lampbrush chromosomes are expensive and time-consuming. In this study, we analyzed the number and distribution of recombination nodules in spermatocytes of the roosters of six chicken breeds using immunolocalization of key proteins involved in chromosome pairing and recombination. We revealed significant effects of breed ([Formula: see text]; [Formula: see text]) and individual ([Formula: see text]; [Formula: see text]) on variation in the number of recombination nodules. Both interbreed and individual variations in recombination rate were almost entirely determined by variation in recombination density on macrochromosomes, because almost all microchromosomes in each breed had one recombination nodule. Despite interbreed differences in the density of recombination nodules, the patterns of their distribution along homologous chromosomes were similar. The breeds examined in this study showed a correspondence between the age of the breed and its recombination rate. Those with high recombination rates (Pervomai, Russian White and Brahma) are relatively young breeds created by crossing several local breeds. The breeds displaying low recombination rate are ancient local breeds: Cochin (Indo-China), Brown Leghorn (Tuscany, Italy) and Russian Crested (the European part of Russia). |
format | Online Article Text |
id | pubmed-6859913 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Copernicus GmbH |
record_format | MEDLINE/PubMed |
spelling | pubmed-68599132019-11-26 Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus Malinovskaya, Lyubov P. Tishakova, Katerina V. Volkova, Natalia A. Torgasheva, Anna A. Tsepilov, Yakov A. Borodin, Pavel M. Arch Anim Breed Original Study The efficiency of natural and artificial selection is critically dependent on the recombination rate. However, interbreed and individual variation in recombination rate in poultry remains unknown. Conventional methods of analysis of recombination such as genetic linkage analysis, sperm genotyping and chiasma count at lampbrush chromosomes are expensive and time-consuming. In this study, we analyzed the number and distribution of recombination nodules in spermatocytes of the roosters of six chicken breeds using immunolocalization of key proteins involved in chromosome pairing and recombination. We revealed significant effects of breed ([Formula: see text]; [Formula: see text]) and individual ([Formula: see text]; [Formula: see text]) on variation in the number of recombination nodules. Both interbreed and individual variations in recombination rate were almost entirely determined by variation in recombination density on macrochromosomes, because almost all microchromosomes in each breed had one recombination nodule. Despite interbreed differences in the density of recombination nodules, the patterns of their distribution along homologous chromosomes were similar. The breeds examined in this study showed a correspondence between the age of the breed and its recombination rate. Those with high recombination rates (Pervomai, Russian White and Brahma) are relatively young breeds created by crossing several local breeds. The breeds displaying low recombination rate are ancient local breeds: Cochin (Indo-China), Brown Leghorn (Tuscany, Italy) and Russian Crested (the European part of Russia). Copernicus GmbH 2019-07-10 /pmc/articles/PMC6859913/ /pubmed/31807651 http://dx.doi.org/10.5194/aab-62-403-2019 Text en Copyright: © 2019 Lyubov P. Malinovskaya et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Original Study Malinovskaya, Lyubov P. Tishakova, Katerina V. Volkova, Natalia A. Torgasheva, Anna A. Tsepilov, Yakov A. Borodin, Pavel M. Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus |
title | Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus |
title_full | Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus |
title_fullStr | Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus |
title_full_unstemmed | Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus |
title_short | Interbreed variation in meiotic recombination rate and distribution in the domestic chicken Gallus gallus |
title_sort | interbreed variation in meiotic recombination rate and distribution in the domestic chicken gallus gallus |
topic | Original Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859913/ https://www.ncbi.nlm.nih.gov/pubmed/31807651 http://dx.doi.org/10.5194/aab-62-403-2019 |
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