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Familial bilateral cryptorchidism is caused by recessive variants in RXFP2

BACKGROUND: Cryptorchidism or failure of testicular descent is the most common genitourinary birth defect in males. While both the insulin-like peptide 3 (INSL3) and its receptor, relaxin family peptide receptor 2 (RXFP2), have been demonstrated to control testicular descent in mice, their link to h...

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Detalles Bibliográficos
Autores principales:	Ayers, Katie, Kumar, Rakesh, Robevska, Gorjana, Bruell, Shoni, Bell, Katrina, Malik, Muneer A, Bathgate, Ross A, Sinclair, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Developmental Defects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860408/ https://www.ncbi.nlm.nih.gov/pubmed/31167797 http://dx.doi.org/10.1136/jmedgenet-2019-106203

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