Leber’s Hereditary Optic Neuropathy as a Promising Disease for Gene Therapy Development

Leber’s hereditary optic neuropathy (LHON) is a relatively common, rapidly progressing inherited optic neuropathy wherein LHON-affected eyes undergo optic nerve atrophy due to retinal ganglion cell (RGC) loss. It is a maternally inherited (or sporadic) mitochondrial disorder caused primarily by muta...

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Detalles Bibliográficos
Autor principal: Karaarslan, Cuneyt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860503/
https://www.ncbi.nlm.nih.gov/pubmed/31605306
http://dx.doi.org/10.1007/s12325-019-01113-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860503/
https://www.ncbi.nlm.nih.gov/pubmed/31605306
http://dx.doi.org/10.1007/s12325-019-01113-2

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