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Leber’s Hereditary Optic Neuropathy as a Promising Disease for Gene Therapy Development
Leber’s hereditary optic neuropathy (LHON) is a relatively common, rapidly progressing inherited optic neuropathy wherein LHON-affected eyes undergo optic nerve atrophy due to retinal ganglion cell (RGC) loss. It is a maternally inherited (or sporadic) mitochondrial disorder caused primarily by muta...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Healthcare
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860503/ https://www.ncbi.nlm.nih.gov/pubmed/31605306 http://dx.doi.org/10.1007/s12325-019-01113-2 |