Cyclosporine A eyedrops with self-nanoemulsifying drug delivery systems have improved physicochemical properties and efficacy against dry eye disease in a murine dry eye model

PURPOSE: We aimed to compare the physicochemical properties and in vivo efficacy of commercially available nanoemulsion cyclosporine A (CsA) eyedrops in benzalkonium chloride (BAC)-induced dry eye disease (DED). METHODS: Particle size analysis was performed on conventional 0.05% CsA (Restasis, C-CsA...

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Detalles Bibliográficos
Autores principales: Bang, Seung Pil, Yeon, Chang Yeor, Adhikari, Nirpesh, Neupane, Sanjiv, Kim, Harim, Lee, Dong Cheol, Son, Myeong Jin, Lee, Hyun Gyo, Kim, Jae-Young, Jun, Jong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860930/
https://www.ncbi.nlm.nih.gov/pubmed/31738791
http://dx.doi.org/10.1371/journal.pone.0224805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6860930/
https://www.ncbi.nlm.nih.gov/pubmed/31738791
http://dx.doi.org/10.1371/journal.pone.0224805

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