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Opioid Overdose With Parkinsonian Features

A 54-year-old man presented to the emergency department with confusion and Parkinsonian features after suspected heroin snorting. He had magnetic resonance imaging of the brain demonstrating isolated symmetric bilateral globus pallidus (GP) restricted diffusion and edema consistent with hypoxic isch...

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Detalles Bibliográficos
Autores principales: Cohen, Paul, Hack, Jason B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861023/
https://www.ncbi.nlm.nih.gov/pubmed/31763612
http://dx.doi.org/10.5811/cpcem.2019.7.43537
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author Cohen, Paul
Hack, Jason B.
author_facet Cohen, Paul
Hack, Jason B.
author_sort Cohen, Paul
collection PubMed
description A 54-year-old man presented to the emergency department with confusion and Parkinsonian features after suspected heroin snorting. He had magnetic resonance imaging of the brain demonstrating isolated symmetric bilateral globus pallidus (GP) restricted diffusion and edema consistent with hypoxic ischemic encephalopathy. In contrast to other anoxic/ischemic insults, where the GP is preferentially spared, autopsy reports on intravenous heroin users have found the GP to be specifically affected, often demonstrating symmetric bilateral lesions. Opioid toxicity should be considered in patients presenting with Parkinsonian features on examination or pallidal lesions on imaging, especially in younger adults where infarction is less common.
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spelling pubmed-68610232019-11-22 Opioid Overdose With Parkinsonian Features Cohen, Paul Hack, Jason B. Clin Pract Cases Emerg Med Images in Emergency Medicine A 54-year-old man presented to the emergency department with confusion and Parkinsonian features after suspected heroin snorting. He had magnetic resonance imaging of the brain demonstrating isolated symmetric bilateral globus pallidus (GP) restricted diffusion and edema consistent with hypoxic ischemic encephalopathy. In contrast to other anoxic/ischemic insults, where the GP is preferentially spared, autopsy reports on intravenous heroin users have found the GP to be specifically affected, often demonstrating symmetric bilateral lesions. Opioid toxicity should be considered in patients presenting with Parkinsonian features on examination or pallidal lesions on imaging, especially in younger adults where infarction is less common. University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2019-10-14 /pmc/articles/PMC6861023/ /pubmed/31763612 http://dx.doi.org/10.5811/cpcem.2019.7.43537 Text en Copyright: © 2019 Cohen et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Images in Emergency Medicine
Cohen, Paul
Hack, Jason B.
Opioid Overdose With Parkinsonian Features
title Opioid Overdose With Parkinsonian Features
title_full Opioid Overdose With Parkinsonian Features
title_fullStr Opioid Overdose With Parkinsonian Features
title_full_unstemmed Opioid Overdose With Parkinsonian Features
title_short Opioid Overdose With Parkinsonian Features
title_sort opioid overdose with parkinsonian features
topic Images in Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861023/
https://www.ncbi.nlm.nih.gov/pubmed/31763612
http://dx.doi.org/10.5811/cpcem.2019.7.43537
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