Thioredoxin-Interacting Protein Promotes Phagosomal Acidification Upon Exposure to Escherichia coli Through Inflammasome-Mediated Caspase-1 Activation in Macrophages

In host defense, it is crucial to maintain the acidity of the macrophage phagosome for effective bacterial clearance. However, the mechanisms governing phagosomal acidification upon exposure to gram-negative bacteria have not been fully elucidated. In this study, we demonstrate that in macrophages e...

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Detalles Bibliográficos
Autores principales: Yoon, Sung-Jin, Jo, Dong Hyun, Park, Seung-Ho, Park, Jun-Young, Lee, Yoo-Kyung, Lee, Moo-Seung, Min, Jeong-Ki, Jung, Haiyoung, Kim, Tae-Don, Yoon, Suk Ran, Chung, Su Wol, Kim, Jeong Hun, Choi, Inpyo, Park, Young-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861186/
https://www.ncbi.nlm.nih.gov/pubmed/31781121
http://dx.doi.org/10.3389/fimmu.2019.02636

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