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Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers

Peptides play a major role in the transmission of information to and from the central nervous system. However, because of their structural complexity, the development of pharmacological peptide-based therapeutics has been challenged by the lack of understanding of endogenous peptide evolution. The t...

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Detalles Bibliográficos
Autores principales: Lovejoy, David A., Hogg, David W., Dodsworth, Thomas L., Jurado, Fernando R., Read, Casey C., D'Aquila, Andrea L., Barsyte-Lovejoy, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861216/
https://www.ncbi.nlm.nih.gov/pubmed/31781029
http://dx.doi.org/10.3389/fendo.2019.00730