Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy

The main pathological mechanism of intervertebral disc degeneration (IVDD) is the programmed apoptosis of nucleus pulposus (NP) cells. Oxidative stress is a significant cause of IVDD. Whether mitophagy is induced by strong oxidative stress in IVDD remains to be determined. This study aimed to invest...

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Detalles Bibliográficos
Autores principales: Xu, Wen-Ning, Zheng, Huo-Liang, Yang, Run-Ze, Liu, Tao, Yu, Wei, Zheng, Xin-Feng, Li, Bo, Jiang, Sheng-Dan, Jiang, Lei-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861227/
https://www.ncbi.nlm.nih.gov/pubmed/31740659
http://dx.doi.org/10.1038/s12276-019-0331-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861227/
https://www.ncbi.nlm.nih.gov/pubmed/31740659
http://dx.doi.org/10.1038/s12276-019-0331-2

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