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Long non-coding RNA GAS5 acts as proliferation “brakes” in CD133+ cells responsible for tumor recurrence

Presence of quiescent, therapy evasive population often described as cancer stem cells (CSC) or tumor initiating cells (TIC) is often attributed to extreme metastasis and tumor recurrence. This population is typically enriched in a tumor as a result of microenvironment or chemotherapy induced stress...

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Detalles Bibliográficos
Autores principales: Sharma, Nikita S., Gnamlin, Prisca, Durden, Brittany, Gupta, Vineet K., Kesh, Kousik, Garrido, Vanessa T., Dudeja, Vikas, Saluja, Ashok, Banerjee, Sulagna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861230/
https://www.ncbi.nlm.nih.gov/pubmed/31740660
http://dx.doi.org/10.1038/s41389-019-0177-4