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FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival
Random-pattern skin flap is commonly used for surgical tissue reconstruction due to its ease and lack of axial vascular limitation. However, ischemic necrosis is a common complication, especially in distal parts of skin flaps. Previous studies have shown that FGF21 can promote angiogenesis and prote...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861244/ https://www.ncbi.nlm.nih.gov/pubmed/31740658 http://dx.doi.org/10.1038/s41419-019-2105-0 |