FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival

Random-pattern skin flap is commonly used for surgical tissue reconstruction due to its ease and lack of axial vascular limitation. However, ischemic necrosis is a common complication, especially in distal parts of skin flaps. Previous studies have shown that FGF21 can promote angiogenesis and prote...

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Detalles Bibliográficos
Autores principales: Zhou, Kailiang, Chen, Huanwen, Lin, Jinti, Xu, Hui, Wu, Hongqiang, Bao, Guodong, Li, Jiafeng, Deng, Xiangyang, Shui, Xiaolong, Gao, Weiyang, Ding, Jian, Xiao, Jian, Xu, Huazi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861244/
https://www.ncbi.nlm.nih.gov/pubmed/31740658
http://dx.doi.org/10.1038/s41419-019-2105-0

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