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Expression of the potential therapeutic target claudin-18.2 is frequently decreased in gastric cancer: results from a large Caucasian cohort study
Gastric cancer (GC) is frequently diagnosed and treated in advanced tumour stages with poor prognosis. Recent studies have identified isoform 2 of the tight junction protein claudin-18 (CLDN18.2) as a promising target in GC therapy. In this study, we aimed to outline the expression of CLDN18.2 and i...
Autores principales: | Dottermusch, Matthias, Krüger, Sandra, Behrens, Hans-Michael, Halske, Christine, Röcken, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861347/ https://www.ncbi.nlm.nih.gov/pubmed/31332522 http://dx.doi.org/10.1007/s00428-019-02624-7 |
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