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Mechanisms of hyperinsulinaemia in apparently healthy non-obese young adults: role of insulin secretion, clearance and action and associations with plasma amino acids

AIMS/HYPOTHESIS: This study aimed to examine the metabolic health of young apparently healthy non-obese adults to better understand mechanisms of hyperinsulinaemia. METHODS: Non-obese (BMI < 30 kg/m(2)) adults aged 18–35 years (N = 254) underwent a stable isotope-labelled OGTT. Insulin sensitivit...

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Detalles Bibliográficos
Autores principales: Hamley, Steven, Kloosterman, Danielle, Duthie, Tamara, Dalla Man, Chiara, Visentin, Roberto, Mason, Shaun A., Ang, Teddy, Selathurai, Ahrathy, Kaur, Gunveen, Morales-Scholz, Maria G., Howlett, Kirsten F., Kowalski, Greg M., Shaw, Christopher S., Bruce, Clinton R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861536/
https://www.ncbi.nlm.nih.gov/pubmed/31489455
http://dx.doi.org/10.1007/s00125-019-04990-y

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