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Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA
Oligoarginine sequences conjugated to a short cancer-targeting peptide (CTP) selective for the prostate-specific membrane antigen (PSMA) receptor was developed for selective small interfering RNA (siRNA) delivery to a human metastatic/castration-resistant prostate cancer (PCa) cell line, which expre...
Autores principales: | Cultrara, Christopher N., Shah, Sunil, Antuono, Gina, Heller, Claudia J., Ramos, Jorge A., Samuni, Uri, Zilberberg, Jenny, Sabatino, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861565/ https://www.ncbi.nlm.nih.gov/pubmed/31739211 http://dx.doi.org/10.1016/j.omtn.2019.10.013 |
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