Cargando…
Chemical Patterns of Proteasome Inhibitors: Lessons Learned from Two Decades of Drug Design
Drug discovery now faces a new challenge, where the availability of experimental data is no longer the limiting step, and instead, making sense of the data has gained a new level of importance, propelled by the extensive incorporation of cheminformatics and bioinformatics methodologies into the drug...
Autores principales: | Guedes, Romina A., Aniceto, Natália, Andrade, Marina A. P., Salvador, Jorge A. R., Guedes, Rita C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862029/ https://www.ncbi.nlm.nih.gov/pubmed/31731563 http://dx.doi.org/10.3390/ijms20215326 |
Ejemplares similares
-
Computational Approaches for the Discovery of Human Proteasome Inhibitors: An Overview
por: Guedes, Romina A., et al.
Publicado: (2016) -
Revisiting Proteasome Inhibitors: Molecular Underpinnings of Their Development, Mechanisms of Resistance and Strategies to Overcome Anti-Cancer Drug Resistance
por: Leonardo-Sousa, Carlota, et al.
Publicado: (2022) -
Exploring the Chemical Space of Urease Inhibitors
to Extract Meaningful Trends and Drivers of Activity
por: Aniceto, Natália, et al.
Publicado: (2022) -
Exploring EZH2-Proteasome Dual-Targeting Drug Discovery through a Computational Strategy to Fight Multiple Myeloma
por: Estrada, Filipe G. A., et al.
Publicado: (2021) -
New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies
por: Guedes, Romina A., et al.
Publicado: (2023)