Repeated Vaginal Exposures to the Common Cosmetic and Household Preservative Methylisothiazolinone Induce Persistent, Mast Cell-Dependent Genital Pain in ND4 Mice

A history of allergies doubles the risk of vulvodynia—a chronic pain condition of unknown etiology often accompanied by increases in numbers of vulvar mast cells. We previously established the biological plausibility of this relationship in mouse models where repeated exposures to the allergens oxaz...

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Detalles Bibliográficos
Autores principales: Arriaga-Gomez, Erica, Kline, Jaclyn, Emanuel, Elizabeth, Neamonitaki, Nefeli, Yangdon, Tenzin, Zacheis, Hayley, Pasha, Dogukan, Lim, Jinyoung, Bush, Susan, Boo, Beebie, Mengistu, Hanna, Kinnamon, Ruby, Shields-Cutler, Robin, Wattenberg, Elizabeth, Chatterjea, Devavani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862067/
https://www.ncbi.nlm.nih.gov/pubmed/31661848
http://dx.doi.org/10.3390/ijms20215361

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