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Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts

Chitosan (CS) and its derivatives show antibacterial and antifungal properties and could help treat and prevent denture stomatitis (DS). Mechanical and surface properties of resilient denture liners were evaluated when modified with CS salts. CS-hydrochloride (CS-HCl) and CS-glutamate (CS-G) were ad...

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Autores principales: Herla, Maike, Boening, Klaus, Meissner, Heike, Walczak, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862088/
https://www.ncbi.nlm.nih.gov/pubmed/31717771
http://dx.doi.org/10.3390/ma12213518
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author Herla, Maike
Boening, Klaus
Meissner, Heike
Walczak, Katarzyna
author_facet Herla, Maike
Boening, Klaus
Meissner, Heike
Walczak, Katarzyna
author_sort Herla, Maike
collection PubMed
description Chitosan (CS) and its derivatives show antibacterial and antifungal properties and could help treat and prevent denture stomatitis (DS). Mechanical and surface properties of resilient denture liners were evaluated when modified with CS salts. CS-hydrochloride (CS-HCl) and CS-glutamate (CS-G) were added to resilient denture liners Ufi Gel P and Coe-Soft at four different concentrations (0.1%, 0.2%, 0.4%, 1% w/w) from which specimens were produced, as well as a control group of each material with no added CS salt. Ten specimens per group (Ø 35 mm, height 6 mm) were manufactured. They were stored in distilled water at 37 °C for a total of 30 days (d). Shore A hardness (SHA) and surface roughness (Ra) were evaluated after 24 h (T1), 7 d (T2), 14 d (T3) and 30 d (T4). Kruskal–Wallis and U-test (Bonferroni-Holm adjusted) were used for statistical analysis (p ≤ 0.05). Ra increased significantly once CS salts were added. SHA increased significantly for some groups, but all specimens fulfilled requirements set by ISO 10139-2:2016. Modification with CS salts does not influence the mechanical properties of the modified resilient denture liners in a clinically relevant manner. Despite the increased roughness, the concept is suitable for further studies. Especially antimicrobial/antibiofilm studies are needed.
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spelling pubmed-68620882019-12-05 Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts Herla, Maike Boening, Klaus Meissner, Heike Walczak, Katarzyna Materials (Basel) Article Chitosan (CS) and its derivatives show antibacterial and antifungal properties and could help treat and prevent denture stomatitis (DS). Mechanical and surface properties of resilient denture liners were evaluated when modified with CS salts. CS-hydrochloride (CS-HCl) and CS-glutamate (CS-G) were added to resilient denture liners Ufi Gel P and Coe-Soft at four different concentrations (0.1%, 0.2%, 0.4%, 1% w/w) from which specimens were produced, as well as a control group of each material with no added CS salt. Ten specimens per group (Ø 35 mm, height 6 mm) were manufactured. They were stored in distilled water at 37 °C for a total of 30 days (d). Shore A hardness (SHA) and surface roughness (Ra) were evaluated after 24 h (T1), 7 d (T2), 14 d (T3) and 30 d (T4). Kruskal–Wallis and U-test (Bonferroni-Holm adjusted) were used for statistical analysis (p ≤ 0.05). Ra increased significantly once CS salts were added. SHA increased significantly for some groups, but all specimens fulfilled requirements set by ISO 10139-2:2016. Modification with CS salts does not influence the mechanical properties of the modified resilient denture liners in a clinically relevant manner. Despite the increased roughness, the concept is suitable for further studies. Especially antimicrobial/antibiofilm studies are needed. MDPI 2019-10-26 /pmc/articles/PMC6862088/ /pubmed/31717771 http://dx.doi.org/10.3390/ma12213518 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Herla, Maike
Boening, Klaus
Meissner, Heike
Walczak, Katarzyna
Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts
title Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts
title_full Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts
title_fullStr Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts
title_full_unstemmed Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts
title_short Mechanical and Surface Properties of Resilient Denture Liners Modified with Chitosan Salts
title_sort mechanical and surface properties of resilient denture liners modified with chitosan salts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862088/
https://www.ncbi.nlm.nih.gov/pubmed/31717771
http://dx.doi.org/10.3390/ma12213518
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