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ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation
Methyl-CpG binding protein 2 (MeCP2) is a multi-function factor involved in locus-specific transcriptional modulation and the regulation of genome architecture, e.g., pericentric heterochromatin (PCH) organization. MECP2 mutations are responsible for Rett syndrome (RTT), a devastating postnatal neur...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862095/ https://www.ncbi.nlm.nih.gov/pubmed/31671722 http://dx.doi.org/10.3390/ijms20215371 |