PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers

Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerativ...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Fabio S. M., Shams, Shahin, Silva, Eduardo A., Stilhano, Roberta S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862231/
https://www.ncbi.nlm.nih.gov/pubmed/31717698
http://dx.doi.org/10.3390/ijms20215328
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author Yamaguchi, Fabio S. M.
Shams, Shahin
Silva, Eduardo A.
Stilhano, Roberta S.
author_facet Yamaguchi, Fabio S. M.
Shams, Shahin
Silva, Eduardo A.
Stilhano, Roberta S.
author_sort Yamaguchi, Fabio S. M.
collection PubMed
description Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries.
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spelling pubmed-68622312019-12-05 PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers Yamaguchi, Fabio S. M. Shams, Shahin Silva, Eduardo A. Stilhano, Roberta S. Int J Mol Sci Review Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries. MDPI 2019-10-25 /pmc/articles/PMC6862231/ /pubmed/31717698 http://dx.doi.org/10.3390/ijms20215328 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yamaguchi, Fabio S. M.
Shams, Shahin
Silva, Eduardo A.
Stilhano, Roberta S.
PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers
title PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers
title_full PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers
title_fullStr PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers
title_full_unstemmed PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers
title_short PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers
title_sort prp and bmac for musculoskeletal conditions via biomaterial carriers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862231/
https://www.ncbi.nlm.nih.gov/pubmed/31717698
http://dx.doi.org/10.3390/ijms20215328
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