Low-affinity neurotrophin receptor p75 of brain-derived neurotrophic factor contributes to cancer-induced bone pain by upregulating mTOR signaling

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Crucial to the development and maintenance of pain sensations is neurotrophin receptor p75 (p75(NTR)), the low affinity receptor of brain-derived neurotrophic factor (BDNF). This receptor is widespread among dorsal root ganglion (DRG) neurons and the spinal cord. Few reports have demonstrated the sp...

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Detalles Bibliográficos
Autores principales: Meng, Xiao-Wen, Jin, Xiao-Hong, Wei, Xiang, Wang, Li-Na, Yang, Jian-Ping, Ji, Fu-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862244/
https://www.ncbi.nlm.nih.gov/pubmed/31777542
http://dx.doi.org/10.3892/etm.2019.8097

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