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Lipophilicity Determination of Quaternary (Fluoro)Quinolones by Chromatographic and Theoretical Approaches

Lipophilicity is a vital physicochemical parameter of a molecule, which affects several biological processes such as absorption, tissue distribution, and pharmacokinetic properties. In this study, evaluation of lipophilicities of a series of novel fluoroquinolone-Safirinium dye hybrids using chromat...

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Detalles Bibliográficos
Autores principales:	Ciura, Krzesimir, Fedorowicz, Joanna, Andrić, Filip, Greber, Katarzyna Ewa, Gurgielewicz, Alina, Sawicki, Wiesław, Sączewski, Jarosław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862250/ https://www.ncbi.nlm.nih.gov/pubmed/31653016 http://dx.doi.org/10.3390/ijms20215288

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